Doxin-200 WS
Doxycycline 10% & tylosin 10% water-soluble powder
- Composition
- Doxycycline hyclate – 100 mg.
- Tylosin tartrate – 100 mg.
Description
The combination of tylosin and doxycycline has additive action. Doxycycline belongs to the group of tetracyclines and has bacteriostatic action against many Gram-positive and Gram-negative bacteria like Bordetella spp., Campylobacter spp., E. coli, Haemophilus spp., Pasteurella spp., Salmonella spp., Staphylococcus spp. and Streptococcus spp. Doxycycline is also active against Chlamydia spp., Mycoplasma spp. and Rickettsia spp. The action of doxycycline is based on inhibition of bacterial protein synthesis. Doxycycline has a great affinity to the lungs and is therefore especially useful for treatment of bacterial respiratory infections. Tylosin is a macrolide antibiotic with a bacteriostatic action against Gram-positive and Gram-negative bacteria like Campylobacter spp., Pasteurella spp., Staphylococcus spp., Streptococcus spp., Brachyspira spp. and Mycoplasma spp.
Indications
Gastrointestinal and respiratory infections caused by tylosin- and doxycycline-sensitive microorganisms, like Bordetella spp., Campylobacter spp., Chlamydia spp., E. coli, Haemophilus spp., Mycoplasma spp., Pasteurella spp., Rickettsia spp., Salmonella spp., Staphylococcus spp., Streptococcus spp. and Brachyspira spp. in calves, sheep, goats, swine and poultry.Contra indications
Hypersensitivity to tetracyclines and/or tylosin.
Administration to animals with a seriously impaired hepatic function.
Concurrent administration of penicillins, cephalosporins, quinolones and cycloserine.
Administration to animals with an active microbial digestion.
Side effects
Discolouration of teeth in young animals.
Hypersensitivity reactions.
Diarrhoea may occur.
Dosage
For oral administration.
Calves, sheep and goats:
Twice daily, 5 gram per 100 kg body weight for 3 - 5 days.
Swine and poultry:
1 kg per 1000 - 2000 litres of drinking water for 3 - 5 days.
Note: for pre-ruminant calves, lambs and kids only.
Withdrawal times
- For meat:
Calves, sheep and goats: 14 days.
Swine: 8 days.
Poultry: 7 days.
Not for use in poultry producing eggs for human consumption.
Packaging
