Description
Oxytetracycline belongs to the group of tetracyclines and acts bacteriostatic against many Gram-positive and Gram-negative bacteria like Bordetella, Campylobacter, Chlamydia, E. coli, Haemophilus, Mycoplasma, Pasteurella, Rickettsia, Salmonella, Staphylococcus and Streptococcus spp. The action of oxytetracycline is based on inhibition of bacterial protein synthesis. Oxytetracycline is mainly excreted in urine, for a small part in bile and in lactating animals in milk.
Indications
Arthritis, gastrointestinal and respiratory infections caused by oxytetracycline sensitive microorganisms, like Bordetella, Campylobacter, Chlamydia, E. coli, Haemophilus, Mycoplasma, Pasteurella, Rickettsia, Salmonella, Staphylococcus and Streptococcus spp. in calves, cattle, goats, sheep and swine.
Contra indications
Hypersensitivity to tetracyclines.
Administration to animals with a seriously impaired renal and/or hepatic function.
Concurrent administration of penicillins, cephalosporins, quinolones and cycloserine.
Side effects
After intramuscular administration local reactions can occur, which disappear in a few days.
Discoloration of teeth in young animals.
Hypersensitivity reactions.
Dosage
For intramuscular or subcutaneous administration:
Full-grown animals : 1 ml per 10 - 20 kg body weight for 3 - 5 days.
Young animals : 2 ml per 10 - 20 kg body weight for 3 - 5 days.
Do not administer more than 20 ml in cattle, more than 10 ml in swine and more than 5 ml in calves, goats and sheep per injection site.
Withdrawal times
- For meat : 12 days.
- For milk : 5 days.