Description
Oxytetracycline belongs to the group of tetracyclines and acts bacteriostatic against many Gram-positive and Gram-negative bacteria like Bordetella, Bacillus, Corynebacterium, Campylobacter, E. coli, Haemophilus, Pasteurella, Salmonella, Staphylococcus and Streptococcus spp. and Mycoplasma, Rickettsia and Chlamydia spp. The mode of action of oxytetracycline is based on inhibition of bacterial protein synthesis. Oxytetracycline is mainly excreted in urine and to a lesser degree in bile and in lactating animals in milk.
Indications
Gastrointestinal and respiratory infections caused by oxytetracycline sensitive bacteria like Bordetella, Bacillus, Corynebacterium, Campylobacter, E. coli, Haemophilus, Pasteurella, Salmonella, Staphylococcus and Streptococcus spp. and Mycoplasma, Rickettsia and Chlamydia spp. in calves, goats, poultry, sheep and swine.
Contra indications
Hypersensitivity to tetracyclines.
Administration to animals with an impaired renal and/or hepatic function.
Concurrent administration of penicillins, cephalosporins, quinolones and cycloserine.
Administration to animals with an active microbial digestion.
Side effects
Discoloration of teeth in young animals.
Hypersensitivity reactions may occur.
Dosage
For oral administration:
Calves, goats and sheep:
Twice daily 1 g per 50 - 100 kg body weight for 3 - 5 days.
Poultry and swine:
1 kg per 5000 litres of drinking water for 3 - 5 days.
Note: for pre-ruminant calves, lambs and kids only.
Withdrawal times
- For meat:
Calves, goats, sheep and swine : 8 days.
Poultry : 6 days.
