Description
Sulfadimidine acts usually bactericidal against many Gram-positive and Gram-negative microorganisms like E. coli, Staphylococcus, Streptococcus, Salmonella, Pasteurella and Eimeria spp.
Sulfadimidin affect bacterial purine synthesis, as a result of which a blockade is accomplished.
Indications
Gastrointestinal, respiratory and urogenital infections caused by sulfadimidine sensitive microorganisms like E.coli, Staphylococcus, Streptococcus and Pasteurella spp. in calves, cattle, goats, poultry, sheep and swine, and coccidiosis caused by Eimeria spp. in poultry.
Contra indications
Hypersensitivity to sulfonamides.
Administration to animals with a seriously impaired renal and/or hepatic function, or with blood dyscrasias.
Side effects
Crystalluria, anaemia, leucopenia and thrombocytopenia.
Dosage
For oral administration:
Calves, cattle,goats and sheep:
10 g per 100 kg body weight for 3 - 7 days.
Swine:
1 kg per 2000 litres of drinking water for 3 - 7 days.
Poultry:
1 kg per 2000 litres of drinking water for 3 days, or according to the 3-2-3 scheme: 3 days on, 2 days off, 3 days on.
Note: For pre-ruminant calves, lambs and kids only.
Withdrawal times
-For meat:
Cattle, calves, sheep, goats: 12 days.
Poultry and swine : 15 days.
-For milk : 5 days.