Amoxicillin is a semisynthetic broad-spectrum penicillin with a bactericidal action against both Gram-positive and Gram-negative bacteria. The spectrum of amoxicillin includes Campylobacter spp., Clostridium spp., Corynebacterium spp., E. coli, Erysipelothrix spp., Haemophilus spp., Pasteurella spp., Salmonella spp., penicillinase-negative Staphylococcus spp. and Streptococcus spp. The bactericidal action is due to inhibition of cell wall synthesis. Amoxicillin is mainly excreted in urine. A major part can also be excreted in bile.
Gastrointestinal, respiratory and urinary tract infections caused by amoxicillin-sensitive microorganisms, like Campylobacter spp., Clostridium spp., Corynebacterium spp., E. coli, Erysipelothrix spp., Haemophilus spp., Pasteurella spp., Salmonella spp., penicillinase-negative Staphylococcus spp. and Streptococcus spp. in calves, sheep, goats, swine and poultry.
Hypersensitivity to amoxicillin.
Administration to animals with a seriously impaired renal function.
Concurrent administration of tetracyclines, chloramphenicol, macrolides and lincosamides.
Administration to animals with an active microbial digestion.
For oral administration.
Calves, sheep and goats:
Twice daily, 5 g per 100 kg body weight for 3 - 5 days.
Swine and poultry:
1 kg per 1000 - 2000 litres of drinking water for 3 - 5 days.
Note: for pre-ruminant calves, lambs and kids only.