Cloxacillin is a beta-lactam antibiotic and is active against penicillin G (benzylpenicillin) resistant staphylococci. It binds to membrane bound proteins known as penicillin-binding proteins (PBPs) that are located beneath the cell wall, thereby disrupting cell wall synthesis. Cloxacillin is bactericidal in its action.
For routine use in cows at drying-off to treat existing intramammary infections and to assist in preventing new infections occurring during the dry period. It is effective against Streptococcus agalactiae, Streptococcus dysgalactiae and other Streptococcus spp., Staphylococcus spp. and Arcanobacterium pyogenes.
Intraclox DC maintains effective antibacterial levels in the dry cow udder for approximately 4 weeks.
Do not use in animals with known hypersensitivity to the active ingredient.
Do not use in lactating animals.
Do not use in cows with a dry period of less than 4 weeks.
For intramammary administration.
1 injector per quarter immediately after the final milking of a lactation.
Before application teats have to be cleaned and disinfected.