Ketosol-100
Ketoprofen 10% injection
- Composition
- Ketoprofen – 100 mg.
Description
Ketoprofen is a derivative of phenylpropionic acid, and belongs to the non-steroidal anti-inflammatory group of drugs. Like all such substances, its principal pharmacological actions are anti-inflammatory, analgesic and anti-pyretic.
Indications
Inflammatory and painful conditions of the bones and joints and musculoskeletal systems in horses. Colic in horses. Respiratory infection and acute clinical mastitis in cattle. Respiratory infection in pigs and Mastitis-Metritis-Agalactia syndrome in sows.Contra indications
Hypersensitivity to ketoprofen.Concurrent administration or administration of other non-steroidal anti-inflammatory drugs (NSAIDs) within 24 hours.
Administration in animals suffering from cardiac, hepatic or renal disease where there is the possibility of gastro-intestinal ulceration or bleeding, where there is evidence of a blood dyscrasia or hypersensitivity to the product. Administration to pregnant mares, because the effects of ketoprofen on fertility, pregnancy or foetal health of horses have not been determined..
Administration to pregnant mares, because the effects of ketoprofen on fertility, pregnancy or foetal health of horses have not been determined.
Side effects
Gastric or renal intolerance due to inhibition of prostaglandin synthesis. No clinical signs have been observed when drugs containing ketoprofen were administered to horses, cattle or pigs when the recommended doses and the recommended durations where exceeded. Horses have been found to tolerate intravenous dosages of ketoprofen of 2.2, 6.6 and 11 mg/kg once daily for 15 consecutive days (i.e. up to 5 times the recommended dose for three times the recommended duration) with no evidence of toxic effects. Ketoprofen is similarly well-tolerated in cattle, where doses of up to 15 mg/kg/day (5 times recommended dose) for 5 consecutive days have been administered without significant adverse effects.
Ketoprofen is well-tolerated in pigs. Doses of 9 mg/kg/day (3 times the recommended dose) for 3 consecutive days have been given with no significant adverse effects.
Dosage
Horses:
1 ml per 45 kg body weight by intravenous injection once daily for up to 3 to 5 days
Cattle:
1 ml per 33 kg body weight by intravenous or deep intramuscular injection once daily for up to 3 days.
Pigs:
1 ml per 33 kg body weight once by deep intramuscular injection.
Withdrawal times
- For meat:
Horses: 1 day
Cattle:
following
intravenous administration: 1 day
following
intramuscular administration: 4 days
Pigs: 4 days
There is no withdrawal period necessary for the milk of treated cattle.
Packaging
