Rymasol-50
Carprofen 5% injection
Composition
- Contains per ml:
-
Carprofen50 mg
Description
Carprofen is a member of the 2-arylpropionic acid group of non-steroidal anti-inflammatory drugs (NSAIDs), and possesses anti-inflammatory, analgesic and antipyretic activity. Carprofen, like most other NSAIDs, is an inhibitor of the enzyme cyclo-oxygenase of the arachidonic acid cascade. However, the inhibition of prostaglandin synthesis by carprofen is slight in relation to its anti-inflammatory and analgesic potency. The precise mode of action is unclear. Studies have shown that carprofen has potent antipyretic activity and significantly reduces the inflammatory response in lung tissue in cases of acute, pyrexic infectious respiratory disease in cattle. Studies in cattle with experimentally induced acute mastitis have shown that carprofen administered intravenously has potent antipyretic activity and improves heart rate and rumen function.
Indications
Rymasol-50 is indicated for the supportive treatment of antimicrobial therapy by reduction of clinical symptoms in acute infectious respiratory diseases and acute mastitis in cattle.
Contraindications
Do not use in cases of hypersensitivity to the active substance or to any of the excipients.
Do not use in animals suffering from cardiac, hepatic or renal impairment.
Do not use in animals suffering from gastrointestinal ulceration or bleeding.
Do not use when there is evidence of blood dyscrasias.
Side Effects
Studies in cattle have shown that a transient local reaction may form at the site of the injection.
Keep away from children.
Some NSAIDs may be highly bound to plasma proteins and compete with other highly bound
drugs, which can lead to toxic effects.
Concurrent administration of nephrotoxic drugs should be avoided.
In case of accidental self-injection seek medical advice.
Wash hands after use. Avoid splashes on the skin and eyes. Irrigate thoroughly with water should this occur. If irritation persists seek medical advice.
Dosage
The product should be given as a single subcutaneous or intravenous injection at a dosage of 1.4 mg carprofen per kg body weight (1 ml per 35 kg bw) in combination with antibiotic therapy, as appropriate.
Withdrawal Times
Meat and offal: 21 days.
Milk: 0 days.
Packaging
