Ceftionel-50
Ceftiofur 5% injection
- Composition
- Ceftiofur (as hydrochloride) – 50 mg.
Description
Ceftiofur is a semisynthetic, third generation, broad-spectrum cephalosporin antibiotic, which is administered to cattle and pigs for control of bacterial infections of the respiratory tract, with additional action against foot rot and acute metritis in cattle. It has a wide spectrum of activity against both Gram-positive and Gram-negative bacteria. It exerts its antibacterial action by inhibition of cell wall synthesis. Ceftiofur is mainly excreted in urine and faeces.
Indications
Cattle: For the treatment of bacterial respiratory disease associated with Mannheimia haemolytica
(former Pasteurella haemolytica), Pasteurella multocida and Histophilus somni (former Haemophilus somnus). For the treatment of acute interdigital necrobacillosis (panaritium, foot rot), associated with Fusobacterium necrophorum and Bacteroides melaninogenicus (Porphyromonas asaccharolytica).
For treatment of the bacterial component of acute postpartum (puerperal) metritis within 10 days after calving associated with Escherichia coli, Arcanobacterium pyogenes and Fusobacterium necrophorum, sensitive to ceftiofur.
Pigs: For the treatment of bacterial respiratory disease associated with Pasteurella multocida, Actinobacillus pleuropneumoniae and Streptococcus suis.
Contra indications
Hypersensitivity to cephalosporins and other β-lactam antibiotics.
Administration to animals with a seriously impaired renal function.
Concurrent administration of tetracyclines, cloramphenicol, macrolides, sulfonamides and lincosamides.
Side effects
Mild hypersensitivity reactions may occur occasionally at the injection site, which subside without further treatment.
Dosage
For subcutaneous or intramuscular administration.
Cattle:
- Bacterial respiratory infections:
1 ml per 50 kg body weight for 3 - 5 days, subcutaneously.
- Acute interdigital necrobacillosis:
1 ml per 50 kg body weight for 3 days, subcutaneously.
- Acute metritis (0 - 10 days postpartum):
1 ml per 50 kg body weight for 5 days, subcutaneously.
Pigs:
- Bacterial respiratory infections:
1 ml per 16 kg body weight for 3 days, intramuscularly.
Shake well before use and do not administer more than 13 ml in cattle per injection site and not more than 4 ml in swine. Successive injections should be administered at different sites.
Withdrawal times
- For meat and offal:
Cattle: 6 days.
Pigs: 2 days.
- For milk: 0 hours.
Packaging
