Description
Glucose is the most important carbohydrate that supplies the body with energy and the necessary metabolites to synthesize amino acids, fatty acids, nucleotides and nucleic acids. It is involved in the formation of carbohydrate reserves (glycogen) both in the liver and in the muscles, and is used in all tissues, including nervous tissue, myocardium, striated muscle tissue (cardiac and skeletal muscles) and liver. Glucose is transported to most cells by specific transport proteins.
Indications
Glucochem-400 is indicated to treat energy deprivation, including hypoglycaemia and clinical ketosis in cattle, horses, sheep, goats, pigs, dogs and cats.
Contra indications
Do not use in case of hyperglycaemia, excessive hydration or hypotonic dehydration.
Do not administer extravenously.
Side effects
Hypertonic glucose solution can irritate peripheral veins, causing topical thrombosis
inflammation. When administered as a single fluid, it may lead to water and electrolyte balance
including hypokalaemia, hypophosphataemia and hypomagnesaemia. Prolonged or rapid dosing of high doses may increase diuresis and cause dehydration.
Overdose may cause hyperglycaemia and osmotic diuresis.
Dosage
For slow intravenous administration only.
The preparation should be slowly administered at 0.5 g glucose per kg body weight per hour:
Cattle, horses: 100 to 125 g of glucose equivalent to 250 to 312.5 ml of the preparation.
Sheep, goats, pigs:
12.5 to 25 g of glucose equivalent to 31 to 62.5 ml of the preparation.
Piglets, dogs, cats:
1.25 to 7.5 g of glucose equivalent to 3 to 19 ml
of preparation.
The preparation should be warmed to body temperature before administration. The preparation is not compatible with aminophylline, soluble barbiturates, erythromycin, hydrocortisone, warfarin, kanamycin, soluble sulfonamides and vitamin B12.
Withdrawal times
- Cattle, horses, sheep, goats, pigs:
Meat and offal: 0 days.
- Cattle, horses, sheep, goats:
Milk: 0 days.
