Intromidium is indicated for treatment and prevention of trypanosomiasis caused by Trypanosoma spp. in camels, horses, cattle, sheep, goats and dogs. Preventive dosage ensures protection for 2 to 4 months. When clinical cases occur, the whole group should be treated.

Intromidium should not be administered subcutaneously.
Avoid concurrent administration of other trypanocidal drugs, particularly diminazene aceturate.
Avoid underdosing.

Individual sensitivity (idiosyncrasy) to Intromidium is possible.

For deep intramuscular or very slow intravenous administration.
Dissolve the content of one sachet of Intromidium in 50 ml or 100 ml of sterile water for injection to obtain a 2% (20 mg/ml) or a 1% (10 mg/ml) solution, respectively. Repeated injections are needed at intervals of 10 to 12 weeks or more, depending on the level of fly challenge.

One sachet is sufficient for the preventive treatment of 8 animals or the curative treatment of 16 animals, weighing 250 kg each.

Camels:
0.5 – 0.75 mg/kg using a 1% solution by very slow intravenous injection.

Horses:
0.5 mg/kg by deep intramuscular injection.

Cattle, sheep and goats:
treatment:
0.25 – 0.5 mg/kg by deep intramuscular injection.
prevention:
0.5 – 1 mg/kg by deep intramuscular injection.

Dogs:
1 mg/kg by deep intramuscular injection.

Deep IM injection should occur preferably in the middle third of the neck in large animals. Doses exceeding 10 ml should be injected at multiple injection sites on each side of the neck. Make sure that the syringe is completely empty before retracting it from the IM injection site. Afterwards, to prevent leakage of Intromidium into subcutaneous tissues, firm pressure must be applied on the injection site. Sheep and goats are injected deep in their thigh muscles.

- For meat: 30 days.
- For milk: 0 days.