Megamast LC
Lactating cows syringe
- Composition
- Contains per 5-g injector:
- Procaine penicillin G – 100 000 IU.
- Streptomycin sulfate – 100 mg.
- Neomycin sulfate – 100 mg.
- Prednisolone – 10 mg.
Description
Procaine penicillin G exerts its effect on multiplying bacteria by interfering with the formation of the cell wall. Streptomycin sulfate and neomycin sulfate are both aminoglycoside antibiotics which, after penetration of the cell envelope, bind to receptors on the 30S subunit of the ribosome. They induce misreading of the genetic code on the messenger ribonucleic acid (mRNA) template, thereby inhibiting bacterial protein synthesis. Prednisolone is a glucocorticoid which has anti-inflammatory properties.
Indications
Megamast LC is indicated for treatment of acute and subacute bovine mastitis in milking cows, accompanied by pain and inflammation caused by bacterial infection sensitive to penicillin, streptomycin and neomycin therapy (e.g. Streptococci, Staphylococcus aureus and E. coli).
Contra indications
Not to be used in animals with known hypersensitivity to the active ingredients or any of the excipients.
Side effects
Penicillins may cause hypersensitivity (allergy) following injection, inhalation, ingestion or skin contact. Hypersensitivity to penicillin may lead to cross reactions to cephalosporins and vice versa. Allergic reactions to these substances may occasionally be serious.
Dosage
For intramammary administration.
The contents of one syringe should be infused gently into each infected quarter via the teat canal immediately after milking, once daily for three consecutive days. Aseptic precautions should be observed at all times.
Withdrawal times
- For meat: 7 days.
- For milk: 108 hours.
Packaging
