Tryponil RTU is indicated for the therapeutic treatment and prophylaxis of trypanosomiasis, babesiosis, mixed haemoprotozoan infections and theileriosis in horses, cattle, buffalos, sheep, goats and dogs.

1. Trypanosomiasis: T. congolense, T. vivax, T. brucei and T. evansi.

2. Babesiosis: B. bovis, B. bigemina, B. ovis, B. motasi, B. canis, B.equi and other Babesia spp.

3. Mixed infections: Mixed infections of Trypanosoma spp. and Babesia spp.

4. Theileriosis: Theileria annulata.

Tryponil RTU offers prophylactic protection against Asiatic (European) Redwater (B. bovis) for 2 weeks, and African Redwater (B. bigemina) for 4 weeks. It can be used as a short-term control in outbreaks with a high morbidity rate.

Treatment of all affected and exposed cattle will bring about rapid but temporary relief.

- Administration to animals with known hypersensitivity to diminazene and/or phenazone
- Administration to animals with an impaired renal and/or hepatic function
- Administration of the product to camels

After overdosing or repeated dosing, toxic disturbances of the central nervous system may develop (salivation, sweating, tremors).
In rare cases, multiple therapeutic doses can produce severe nervous signs and prominent haemorrhagic and malacic lesions of the cerebellum and thalamus in cattle and dogs.
After multiple therapeutic doses, degenerative fatty changes can occur in liver, kidneys, myocardium and muscles.

For deep intramuscular administration.
The usual therapeutic dose is 1 ml per 20 kg body weight (3.5 mg/kg). For infections with T. brucei, T. evansi and Theileria annulata, this dose should be doubled (1 ml per 10 kg).
For infections due to resistant strains, the dose may be increased to 8 mg/kg body weight (1 ml per 8.75 kg).
Do not exceed a total dose of 4 g (57 ml) per animal. When large quantities of Tryponil RTU solution are administered, it is advisable to divide the amount to be injected over multiple sites in order to avoid local pain reactions.

- For meat: 21 days.
- For milk: 3 days.