Amprolin-300 WS
Amprolium 30% water-soluble powder
- Composition
- Contains per gram powder:
-
Amprolium hydrochloride300 mg.
Description
Amprolium is a coccidiostat (antiprotozoal) used for the treatment and prevention of coccidiosis, predominantly in chickens (broilers and breeders) and other fowl such as turkeys, with activity against Eimeria spp., especially Eimeria tenella and Eimeria necatrix. It is a thiamine (vitamin B1) analogue and its pharmacological effect relies on competitive inhibition of thiamine uptake. Amprolium competitively inhibits the active transport of thiamine in isolated second-generation schizonts of Eimeria spp., and in chicken intestinal cells. Upon ingestion of amprolium, the coccidia experience thiamine deficiency and starve from malnutrition.
Indications
Amprolin-300 WS is indicated for coccidiosis caused by coccidia susceptible to amprolium (Eimeria spp.) or gastrointestinal infections for which it is therapeutically or prophylactically indicated to administer amprolium in calves, sheep, goats and poultry.Contra indications
None known.
Side effects
None known.
Dosage
For oral administration:
- Calves, sheep and goats:
Preventive: 1 gram per 60 kg body weight through drinking water or milk for 21 days.
Curative: 1 gram per 30 kg body weight through drinking water or milk for 5 days.
- Poultry:
Preventive: 1 kg Amprolin-300 WS per 5000 litres of drinking water for 1-2 weeks.
Curative: 1 kg Amprolin-300 WS per 1250-2500 litres of drinking water for 5-7 days.
Note: mix Amprolin-300 WS daily with fresh water. In severe cases curative treatment may be followed by preventive treatment.
Withdrawal times
- For meat:
Calves, sheep and goats : 3 days.
Poultry : 0 days.
- For eggs : 0 days.
Packaging
